Prescription medications carry risks and side effects. A licensed physician will review your health history before prescribing. Prescriptions are never guaranteed. Individual results vary.
Men's Health · ED Treatment

Silde-
nafil

Generic sildenafil — the FDA-approved generic of Viagra® — proven for 25+ years
82%Clinical success rate
30–60 minTime to onset
4–6 hrsDuration of action
Start for $49/month →
Physician consultation included · Discreet delivery
Sildenafil blue pills
Licensed Physicians 25+ Years of Clinical Data Discreet Packaging HIPAA Compliant
The Science

How sildenafil works

ED affects approximately 30 million men in the United States. Sildenafil (the active ingredient in Viagra®) is a PDE5 inhibitor — it works by relaxing smooth muscle and increasing blood flow to the penis, enabling natural erections in response to sexual stimulation.

01 · Mechanism
Blocks PDE5 enzyme
Sildenafil inhibits the PDE5 enzyme, which normally breaks down cGMP — the chemical that causes smooth muscle relaxation and increased blood flow.
02 · Blood flow
Enhances circulation
With PDE5 blocked, cGMP levels rise, relaxing penile smooth muscle and allowing increased blood flow when sexually stimulated.
03 · Result
Natural, reliable erections
Sildenafil doesn't cause erections on its own — it enables them in response to sexual stimulation, as nature intended. Works in 30–60 minutes.
Dosage Options

Your physician finds the right dose

Sildenafil comes in three doses. Your physician will start you at the appropriate dose based on your health profile, age, and current medications — adjusting as needed.

25mg
Starting dose for men over 65, or those on other medications. Lower side effect profile.
100mg
Maximum dose for men who don't get adequate response at 50mg.
30–60 min
Take before sexual activity
4–6 hours
Window of effectiveness
As-needed
Not a daily medication
Empty stomach
Works faster without food
Safety Profile

Side effects & safety

Sildenafil has one of the most extensive safety databases of any medication — with over 25 years of real-world use in hundreds of millions of patients. Most side effects are mild and transient.

Common (usually mild)
  • Headache (10–16% of users)
  • Facial flushing (warmth/redness)
  • Nasal congestion
  • Mild indigestion or upset stomach
  • Temporary blue-tinted vision at high doses (rare)
Important contraindications
  • Do NOT take with nitrate medications (severe blood pressure drop)
  • Caution with alpha-blockers (blood pressure medications)
  • Avoid with grapefruit juice (increases medication levels)
  • Not for men with recent heart attack or stroke
  • Physician will screen for all contraindications
Comparison

Sildenafil vs Tadalafil

Both medications work similarly, but differ in duration and dosing. Sildenafil is ideal for planned encounters; tadalafil is better for spontaneity and daily use.

SildenafilTadalafil
Brand equivalentViagra®Cialis®
Clinical success rate82%85%
Time to onset30–60 minutes30–60 minutes
Duration4–6 hoursUp to 36 hours
DosingAs-needed onlyDaily or as-needed
Food interactionFaster on empty stomachMinimal food effect
Best forPlanned intimacySpontaneous activity
NuvaMed price$49/month$49/month
Common Questions

Sildenafil FAQs

Generic sildenafil is the FDA-approved generic of Viagra®. It contains the same active ingredient, at the same dosages, and meets the same FDA approval standards. NuvaMed physicians prescribe it after reviewing your health history and determining it is appropriate. Viagra® is a trademark of Pfizer. NuvaMed is not affiliated with Pfizer.
Sildenafil typically starts working within 30–60 minutes, and works best on an empty stomach. Effects last 4–6 hours.
Sildenafil should never be combined with nitrate medications. Your physician will review your full medication list and health history before prescribing to check for contraindications like alpha-blockers.
Sildenafil is available in 25mg, 50mg, and 100mg doses. Your physician selects the starting dose based on your age, health profile, and current medications, and can adjust it over time.
Yes. You can cancel or pause your subscription anytime from your patient portal or by emailing help@nuvamed.org.
Get Started

Start your sildenafil program today

A licensed physician consultation, the right prescription, and discreet delivery — all for less than a single Viagra® pill at the pharmacy.

Sildenafil Program · Starting at
$49/month
Begin My Intake →
Physician evaluation included · Discreet packaging · Cancel anytime
Stay Informed
Get your men's health guide
Enter your email and we'll send you a free guide on physician-supervised men's health — what to expect, how to qualify, and how to get started.
Ready to get started? Free assessment — takes 5 minutes.
Get My Plan →